What does the term 'proliferation' refer to in the context of cancer?

The term 'proliferation' in the context of cancer refers specifically to the rapid increase in the number of cells. This process is significant because cancer cells often replicate uncontrollably, leading to the formation of tumors and the potential spread of cancer throughout the body. In a healthy context, cell proliferation is tightly regulated, ensuring that new cells grow as old ones die. However, in cancer, this regulation is lost, resulting in an excessive number of cells that can accumulate and disrupt normal bodily functions. Understanding proliferation is crucial for recognizing how cancer develops and progresses.