What critical condition may lead to the proliferation of opportunistic infections?

The proliferation of opportunistic infections is primarily associated with a weakened immune system. When the immune system is compromised, whether due to illness, immunosuppressive medications, nutritional deficiencies, or other health conditions, the body's ability to fight off infections diminishes. This creates an environment where opportunistic pathogens, which typically do not cause disease in a healthy individual, can thrive and lead to infections.

A strengthened immune response, increased physical activity, and low stress levels generally help to bolster the immune system, enhancing its ability to combat infections. These conditions promote overall health and resilience against pathogens. In contrast, a weak immune system poses a significant risk for the individual, making them more susceptible to infections that they would otherwise be able to fend off.