Surgical removal of regional lymph nodes can result in which condition?

Lymphedema is a condition that can arise from the surgical removal of regional lymph nodes, particularly when the lymphatic drainage pathway is disrupted. This surgical intervention, often performed during cancer treatment to prevent the spread of disease, can lead to an accumulation of lymph fluid in the tissues. The lymphatic system is essential for draining excess fluid, proteins, and waste products from the interstitial spaces; when lymph nodes are removed, this drainage function is compromised.

As a result, fluid can build up in the surrounding tissues, causing swelling known as lymphedema. This swelling might occur in the area affected by surgery or, in some cases, may manifest in other areas connected to the affected lymphatic system. The condition can lead to discomfort, reduced mobility, and increased risk of infections in the swollen areas, emphasizing the importance of understanding post-surgical outcomes in patients with a history of lymph node removal.